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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Sigma-1 Receptor Antibodies

          Invitrogen

          Sigma-1 Receptor Polyclonal Antibody

          Advanced Verification
          1 Reference
          View all (11) Sigma-1 Receptor antibodies

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          Cite Sigma-1 Receptor Polyclonal Antibody

          • Antibody Testing Data (4)
          • Advanced Verification (1)
          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          Sigma-1 Receptor Antibody (PA5-30372) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using SIGMAR1 (Product # PA5-30372) antibody at 1:100 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Antibody

          Product Details

          PA5-30372

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Zebrafish

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human SIGMAR1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.24 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 20% glycerol

          Contains

          0.025% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2547846

          Product Specific Information

          Recommended positive controls: 293T.

          Predicted reactivity: Mouse (94%), Rat (96%), Rhesus Monkey (100%), Bovine (97%), Guinea pig (96%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Aging-associated gene 8 protein; AL024364; mSigmaR1; opioid receptor, sigma 1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; Sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; Sigma-1 Receptor; sigma1 receptor; Sigma1-receptor; sigma1R; SR BP; SR-BP; SR31747 binding protein 1; SR31747-binding protein

          View more View less

          Gene Aliases: AAG8; ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SIGMAR1; SR-BP; SR-BP1; SRBP; zgc:56378

          View more View less

          UniProt ID: (Human) Q99720, (Mouse) O55242, (Zebrafish) Q7ZWG9

          View more View less

          Entrez Gene ID: (Human) 10280, (Mouse) 18391, (Zebrafish) 393952

          View more View less

          Function(s)
          opioid receptor activity drug binding receptor activity protein binding transmembrane signal receptor
          Process(es)
          lipid transport nervous system development opioid receptor signaling pathway regulation of neuron apoptotic process protein homotrimerization transport response to wounding
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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