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Fabgennix
Skn1 Polyclonal Antibody, Biotin
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Product Details
POU2F3-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids within region 150-200 on human POU2F3 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer with 20% glycerol, 0.5% BSA
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Quantity: 100 µg IgG per vial
Target Information
POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; Rov 1 pou-homeodomain protein; Skn-1a, Epoc-1; Transcription factor PLA-1; Transcription factor Skn-1; unnamed protein product
Gene Aliases: Epoc-1; OCT-11; OCT11; OTF-11; OTF11; PLA-1; PLA1; POU2F3; Skn-1; Skn-1a; Skn1
UniProt ID: (Human) Q9UKI9, (Rat) P42571
Entrez Gene ID: (Human) 25833, (Rat) 116544
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein dimerization activity
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
epidermis development
keratinocyte differentiation
wound healing
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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