Immunogen sequence: APSDPRLRQF LQKSLAAAAG KQELAKYFLA ELLSEPNQTE NDALEPEDLS QAAEQDEMRL ELQRSANSNP AMAPRERKAG CKN
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antrin; Growth hormone release-inhibiting factor; prepro-somatostatin; preprosomatostatin; SMST; Somatostatin; Somatostatin-14; Somatostatin-28
Gene Aliases: SMST; SOM; SRIF; SS; SST