This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cystine-knot containing secreted protein; Ectodermal BMP inhibitor; Ectodin; sclerostin domain containing 1; Sclerostin domain-containing protein 1; Sclerostin-like protein; USAG-1; Uterine sensitization-associated gene 1 protein; uterine sensitization-associated protein 1; uterine sensitization-associated protein 1-like; uterine sensitization-associated protein-1; Wnt-signaling modulator
Gene Aliases: 0610006G05Rik; BOS_4057; CDA019; DAND7; ECTODIN; SOSTDC1; Sostl; USAG-1; USAG1; Wise