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Proteintech
Spartin/SPG20 Polyclonal Antibody
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Product Details
13791-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Spartin, SPG20 Fusion Protein Ag4815 (1-350 aa encoded by BC047083)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEQEPQNGE PAEIKIIREA YKKAFLFVNK GLNTDELGQK EEAKNYYKQG IGHLLRGISI SSKESEHTGT GWESARQMQQ KMKETLQNVR TRLEILEKGL ATSLQNDLQE VPKLYPEFPP KDMCEKLPEP QSFSSAPQHA EVNGNTSTPS AGAVAAPASL SLPSQSCPAE APPAYTPQAA EGHYTVSYGT DSGEFSSVGE EFYRNHSQPP PLETLGLDAD ELILIPNGVQ IFFVNPAGEV SAPSYPGYLR IVRFLDNSLD TVLNRPPGFL QVCDWLYPLV PDRSPVLKCT AGAYMFPDTM LQAAGCFVGV VLSSELPEDD RELFEDLLRQ MSDLRLQANW NRAEEENEFQ I (1-350 aa encoded by BC047083)
Target Information
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Spartin; spastic paraplegia 20 (Troyer syndrome); spastic paraplegia 20 (Troyer syndrome) homolog; spastic paraplegia 20 (Troyer syndrome) isoform SPG20_1; spastic paraplegia 20 (Troyer syndrome) isoform SPG20_2; Spastic paraplegia 20 protein; spastic paraplegia 20, spartin (Troyer syndrome) homolog; spastic paraplegia autosomal recessive Troyer syndrome; Trans-activated by hepatitis C virus core protein 1; unnamed protein product
Gene Aliases: AI840044; C79168; KIAA0610; mKIAA0610; SPART; SPARTIN; SPG20; TAHCCP1
UniProt ID: (Human) Q8N0X7, (Mouse) Q8R1X6
Entrez Gene ID: (Human) 23111, (Rat) 295053, (Mouse) 229285
abscission
negative regulation of BMP signaling pathway
lipid particle organization
negative regulation of collateral sprouting in absence of injury
neuromuscular process
cell division
regulation of mitochondrial membrane potential
adipose tissue development
cytokinesis
lipid metabolic process
lipid transport
lipid catabolic process
BMP signaling pathway
collateral sprouting in absence of injury
lipophagy
midbody abscission
regulation of biological quality
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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