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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Residues 2150 and 2200 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ).|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Immunoprecipitation (IP)||2-5 µg/mg lysate|
|Western Blot (WB)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is not recommended for Western blot analysis.
Suggested positive control: HeLa whole cell lysate.
Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
beta-III spectrin; glutamate transporter EAAT4-associated protein 41; GTRAP41; SCA5; spectrin beta chain, brain 2; spectrin beta III sigma 2; spectrin, beta, non-erythrocytic 2; spectrin, non-erythroid beta chain 2; spinocerebellar ataxia 5 protein
GTRAP41; KIAA0302; SCA5; SCAR14; SPTBN2