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Stargazin Antibody (ACC-012-GP200UL) in WB
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4)brain lysates: - 1,2. Guinea pig Anti-Stargazin Antibody (#ACC-012-GP), (1:500).3,4. Guinea pig Anti-Stargazin Antibody , preincubated with Stargazin Blocking Peptide (#BLP-CC012).
Product Details
ACC-012-GP200UL
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Guinea pig
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RATDYLQASAITRIPS, corresponding to amino acid residues 213-228 of mouse CaV gamma 2, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CaV gamma 2; MGC123981; MGC138502; MGC138504; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; Voltage-dependent calcium channel gamma-2 subunit
Gene Aliases: AW060990; B230105C07Rik; B930041E13Rik; Cacng2; Ipr328; stargazer; stargazin; Stg; wag; waggler
UniProt ID: (Rat) Q71RJ2, (Mouse) O88602
Entrez Gene ID: (Rat) 84347, (Mouse) 12300
neuromuscular junction development
transmission of nerve impulse
regulation of ion transmembrane transport
regulation of membrane potential
neurological system process
membrane depolarization
membrane hyperpolarization
calcium ion transmembrane transport
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
transport
ion transport
calcium ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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