Proteintech

Stathmin 1 Polyclonal Antibody

Stathmin 1 Antibody in Immunocytochemistry (ICC/IF)

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Stathmin 1 Antibody (11157-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 11157-1-AP (Stathmin 1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Stathmin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Stathmin 1 Antibody in Western Blot (WB)

Product Image Gallery

Product Details

11157-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 16 publications 16 publications

Immunohistochemistry (IHC)

View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Stathmin 1 Fusion Protein Ag1633 (1-149 aa encoded by BC014353)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MASSDIQVK ELEKRASGQA FELILSPRSK ESVPEFPLSP PKKKDFSLEE IQKKLEAAEE RRKSHEAEVL KQLAEKREHE KEVLQKAIEE NNNFSKMAEE KLTHKMEANK ENREAQMAAK LERLREKDKH IEEVRKNKES KDPADETEAD (1-149 aa encoded by BC014353)

Target Information

Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.

Cell reports

Almeida AC,Soares-de-Oliveira J,Drpic D,Cheeseman LP,Damas J,Lewin HA,Larkin DM,Aguiar P,Pereira AJ,Maiato H

Tue Apr 05 00:00:00 UTC 2022

The prognostic role of a phospho-Stathmin 1 signature in breast cancer treated with neoadjuvant chemotherapy.

Gland surgery

Xie Z,Zhen T,Lin Y,Shao N,Kuang X

Tue Nov 01 00:00:00 UTC 2022

MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis.

Frontiers in oncology

Li H,Han G,Li X,Li B,Wu B,Jin H,Wu L,Wang W

Sun Apr 24 00:00:00 UTC 2022

Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas.

Cell stem cell

Lodestijn SC,van den Bosch T,Nijman LE,Moreno LF,Schlingemann S,Sheraton VM,van Neerven SM,Koning JJ,Vieira Braga FA,Paauw NJ,Lecca MC,Lenos KJ,Morrissey E,Miedema DM,Winton DJ,Bijlsma MF,Vermeulen L

Thu Nov 04 00:00:00 UTC 2021

Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas.

Cell stem cell

Lodestijn SC,van den Bosch T,Nijman LE,Moreno LF,Schlingemann S,Sheraton VM,van Neerven SM,Koning JJ,Vieira Braga FA,Paauw NJ,Lecca MC,Lenos KJ,Morrissey E,Miedema DM,Winton DJ,Bijlsma MF,Vermeulen L

Thu Nov 04 00:00:00 UTC 2021

Dermal Fibroblast Migration and Proliferation Upon Wounding or Lipopolysaccharide Exposure is Mediated by Stathmin.

Frontiers in pharmacology

Cen R,Wang L,He Y,Yue C,Tan Y,Li L,Lei X

Wed Feb 16 00:00:00 UTC 2022

Protein Nanoparticle-Related Osmotic Pressure Modifies Nonselective Permeability of the Blood-Brain Barrier by Increasing Membrane Fluidity.

International journal of nanomedicine

Li C,Chen L,Wang Y,Wang T,Di D,Zhang H,Zhao H,Shen X,Guo J

Fri Mar 26 00:00:00 UTC 2021

HIV-1 exposure promotes PKG1-mediated phosphorylation and degradation of stathmin to increase epithelial barrier permeability.

The Journal of biological chemistry

Xie W,Chen M,Zhai Z,Li H,Song T,Zhu Y,Dong D,Zhou P,Duan L,Zhang Y,Li D,Liu X,Zhou J,Liu M

Mon Aug 23 00:00:00 UTC 2021

The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.

BMC cancer

Yang X,Li S,Wu Y,Ge F,Chen Y,Xiong Q

Wed Apr 15 00:00:00 UTC 2020

The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.

BMC cancer

Yang X,Li S,Wu Y,Ge F,Chen Y,Xiong Q

Wed Apr 15 00:00:00 UTC 2020

Developmental dynamics of the periventricular parietal crossroads of growing cortical pathways in the fetal brain - In vivo fetal MRI with histological correlation.

NeuroImage

Milos RI,Jovanov-Milošević N,Mitter C,Bobić-Rasonja M,Pogledic I,Gruber GM,Kasprian G,Brugger PC,Weber M,Judaš M,Prayer D

Wed Apr 15 00:00:00 UTC 2020

Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice.

Journal of proteome research

Zhang J,Tang N,Zhao Y,Zhao R,Fu X,Zhao D,Zhao Y,Huang L,Li C,Qiu Y,Xue B,Fang L

Fri Apr 03 00:00:00 UTC 2020

KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.

Oncogene

Zhao L,Zhang D,Shen Q,Jin M,Lin Z,Ma H,Huang S,Zhou P,Wu G,Zhang T

Fri Feb 01 00:00:00 UTC 2019

KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.

Oncogene

Zhao L,Zhang D,Shen Q,Jin M,Lin Z,Ma H,Huang S,Zhou P,Wu G,Zhang T

Fri Feb 01 00:00:00 UTC 2019

Perinatal exposure to nonylphenol impairs dendritic outgrowth of cerebellar Purkinje cells in progeny.

Chemosphere

You M,Gu W,Li M,Qiu Z,Li S,Jiang Z,Yao D,Xu Y,Wang Y

Thu Nov 01 00:00:00 UTC 2018

Perinatal exposure to nonylphenol impairs dendritic outgrowth of cerebellar Purkinje cells in progeny.

Chemosphere

You M,Gu W,Li M,Qiu Z,Li S,Jiang Z,Yao D,Xu Y,Wang Y

Thu Nov 01 00:00:00 UTC 2018

Transcriptome sequencing of the naked mole rat (Heterocephalus glaber) and identification of hypoxia tolerance genes.

Biology open

Xiao B,Li L,Xu C,Zhao S,Lin L,Cheng J,Yang W,Cong W,Kan G,Cui S

Fri Dec 15 00:00:00 UTC 2017

Transcriptome sequencing of the naked mole rat (Heterocephalus glaber) and identification of hypoxia tolerance genes.

Biology open

Xiao B,Li L,Xu C,Zhao S,Lin L,Cheng J,Yang W,Cong W,Kan G,Cui S

Fri Dec 15 00:00:00 UTC 2017

Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.

Frontiers in cellular and infection microbiology

Zan J,Liu S,Sun DN,Mo KK,Yan Y,Liu J,Hu BL,Gu JY,Liao M,Zhou JY

Wed Dec 27 00:00:00 UTC 2017

Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.

Frontiers in cellular and infection microbiology

Zan J,Liu S,Sun DN,Mo KK,Yan Y,Liu J,Hu BL,Gu JY,Liao M,Zhou JY

Wed Dec 27 00:00:00 UTC 2017

Stathmin is enriched in the developing corticospinal tract.