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Staufen Polyclonal Antibody
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Product Details
BS-9877R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Horse,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Staufen, amino acids 448-488.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 1; protein phosphatase 1, regulatory subunit 150; RNA binding protein; alternatively spliced; RP3-470L14.2; staufen RNA binding protein homolog 1; staufen, RNA binding protein, homolog 1; unnamed protein product
Gene Aliases: 5830401L18Rik; AW549911; C85792; PPP1R150; STAU; STAU1
UniProt ID: (Human) O95793, (Mouse) Q9Z108
Entrez Gene ID: (Human) 6780, (Chicken) 419213, (Horse) 100056924, (Rat) 84496, (Mouse) 20853
intracellular mRNA localization
positive regulation of viral genome replication
positive regulation by virus of viral protein levels in host cell
lncRNA-mediated post-transcriptional gene silencing
germ cell development
cellular response to oxidative stress
protein localization to synapse
modulation of synaptic transmission
anterograde dendritic transport of messenger ribonucleoprotein complex
modification of postsynaptic structure
positive regulation of long-term synaptic potentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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