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Invitrogen
Synapsin 1 Polyclonal Antibody
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FIGURE: 1 / 3
Synapsin 1 Antibody (PA1-4673) in WB
Western blot was performed using anti-Synapsin1 Polyclonal Antibody (Product # PA1-4673) and a 78 kDa band was observed corresponding to Synapsin1 was observed across cell lines and tissues tested except Mouse and Rat Lung, Mouse Heart and Raji which are reported to be negative. Whole cell extracts of (30ug lysate) of IMR-32 (Lane 1), PC-12 (Lane 2), Raji (Lane 8), tissue extracts of Mouse Brain (Lane 3), Rat Brain (Lane 4), Mouse Lung (Lane 5), Rat Lung (Lane 6) and Mouse Heart (Lane 7) were electrophoresed using Novex® NuPAGE® 4-12 % Bis... View More
Product Details
PA1-4673
Applications
Tested Dilution
Publications
Product Specifications
Published species
C. elegans,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Native protein purified from bovine brain
Conjugate
Form
Lyophilized
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is specific for the ~78 kDa Synapsin I protein doublet. Immunolabeling is blocked by preadsorption of the antibody with the protein used to generate the antibody.
Reconstitute with 50 µL of PBS.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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