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|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from aa region 440-490 of mouse Synapsin III conjugated to an immunogenic carrier protein was used as the antigen|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Reconstitute with 100 ul of distilled water.
This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The schizophrenia risk gene product miR-137 alters presynaptic plasticity.
OSS00018W was used in western blot to characterize induced human neurons harboring alleles of four disease-associated single nucleotide polymorphisms in MIR137
|Siegert S,Seo J,Kwon EJ,Rudenko A,Cho S,Wang W,Flood Z,Martorell AJ,Ericsson M,Mungenast AE,Tsai LH||Nature neuroscience (18:1008)||2015|
Syn3; Synapsin 3; Synapsin III; synapsin IIIa; Synapsin-3