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Proteintech
Synaptopodin Polyclonal Antibody
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Product Details
21064-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synaptopodin Fusion Protein Ag15089 (580-929 aa encoded by BC146665)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SPPSYSVLY PSSDPKSSHL KGQAVPASKT GILEESMARR GSRKSMFTFV EKPKVTPNPD LLDLVQTADE KRRQRDQGEV GVEEEPFALG AEASNFQQEP APRDRASPAA AEEVVPEWAS CLKSPRIQAK PKPKPNQNLS EASGKGAELY ARRQSRMEKY VIESSSHTPE LARCPSPTMS LPSSWKYPTN APGAFRVASR SPARTPPASL YHGYLPENGV LRPEPTKQPP YQLRPSLFVL SPIKEPAKVS PRAASPAKPS SLDLVPNLPK GALPPSPALP RPSRSSPGLY TSPGQDSLQP TAVSPPYGGD ISPVSPSRAW SPRAKQAPRP SFSTRNAGIE AQVWKPSFCF K (580-929 aa encoded by BC146665)
Target Information
SYNPO (Synaptopodin) is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin associated protein; Synaptopodin; unnamed protein product
Gene Aliases: 9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661; KIAA1029; SYNPO; SYNPO1
UniProt ID: (Human) Q8N3V7, (Rat) Q9Z327
Entrez Gene ID: (Human) 11346, (Rat) 60324, (Mouse) 104027
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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