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          • Primary Antibodies ›
          • HERV-FRD Antibodies

          Fabgennix

          Syncytin 2 Polyclonal Antibody, FITC

          View all (11) HERV-FRD antibodies

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          Cite Syncytin 2 Polyclonal Antibody, FITC

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          Syncytin 2 Polyclonal Antibody, FITC

          Product Details

          SYCY2-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 380-430 on mouse Envelope glycoprotein syncytin-B protein.
          3D Epitope / Immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: envelope glycoprotein syncytin-A; envelope glycoprotein syncytin-B; FLJ41944; FLJ90611; MGC87585; placenta-specific/fusogenic; Synb; Syncytin-B; Syncytin2

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          Gene Aliases: D930020E02Rik; Gm52; Synb; syncytin-B

          View more View less

          UniProt ID: (Mouse) Q8BI41

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          Entrez Gene ID: (Rat) 288602, (Mouse) 239167

          View more View less

          Function(s)
          molecular_function viral or transposable element protein
          Process(es)
          syncytium formation by plasma membrane fusion syncytium formation labyrinthine layer development labyrinthine layer blood vessel development
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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