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Proteintech
Syntaxin 17 Polyclonal Antibody
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Product Details
17815-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Syntaxin 17 Fusion Protein Ag12134 (1-216 aa encoded by BC111009)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSEDEEKVK LRRLEPAIQK FIKIVIPTDL ERLRKHQINI EKYQRCGIWD KLHEEHINAG RTVQQLRSNI REIEKLCLKV RKDDLVLLKR MIDPVKEEAS AATAEFLQLH LESVEELKKQ FNDEETLLQP PLTRSMTVGG AFHTTEAEAS SQSLTQIYAL PEIPQDQNAA ESWETLEADL IELSQLVTDF SLLVNSQQEK IDSIADHVNS AAVNVEE (1-216 aa encoded by BC111009)
Target Information
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Syntaxin-17; unnamed protein product
Gene Aliases: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351; STX17
UniProt ID: (Human) P56962, (Rat) Q9Z158, (Mouse) Q9D0I4
Entrez Gene ID: (Human) 55014, (Rat) 252853, (Mouse) 67727
intracellular protein transport
exocytosis
ER to Golgi vesicle-mediated transport
vesicle fusion
autophagy
Golgi organization
vesicle-mediated transport
autophagosome membrane docking
protein localization to pre-autophagosomal structure
vesicle docking
autophagosome-lysosome fusion
endoplasmic reticulum-Golgi intermediate compartment organization
autophagosome maturation
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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