Proteintech

Syntaxin 17 Polyclonal Antibody

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Syntaxin 17 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HepG2 cells using 17815-1-AP (Syntaxin 17 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Syntaxin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney tissue slide using 17815-1-AP (Syntaxin 17 antibody at dilution of 1:50 (under 40x lens).

Syntaxin 17 Antibody in Western Blot (WB) — Human testis tissue were subjected to SDS PAGE followed by western blot with 17815-1-AP (Syntaxin 17 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Syntaxin 17 Antibody in Immunoprecipitation (IP) — IP result of anti-Syntaxin 17 (IP:17815-1-AP, 4ug; Detection:17815-1-AP 1:1000) with HepG2 cells lysate 3600ug.

Product Details

17815-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 26 publications 26 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 9 publications 9 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 5 publications 5 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Syntaxin 17 Fusion Protein Ag12134 (1-216 aa encoded by BC111009)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: MSEDEEKVK LRRLEPAIQK FIKIVIPTDL ERLRKHQINI EKYQRCGIWD KLHEEHINAG RTVQQLRSNI REIEKLCLKV RKDDLVLLKR MIDPVKEEAS AATAEFLQLH LESVEELKKQ FNDEETLLQP PLTRSMTVGG AFHTTEAEAS SQSLTQIYAL PEIPQDQNAA ESWETLEADL IELSQLVTDF SLLVNSQQEK IDSIADHVNS AAVNVEE (1-216 aa encoded by BC111009)

Target Information

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Syntaxin-17

Gene Aliases: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351; STX17

UniProt ID: (Human) P56962, (Rat) Q9Z158, (Mouse) Q9D0I4

Entrez Gene ID: (Human) 55014, (Rat) 252853, (Mouse) 67727

Molecular Function: SNARE protein

Function(s)

intracellular protein transport ER to Golgi vesicle-mediated transport vesicle fusion Golgi organization protein localization to pre-autophagosomal structure vesicle docking endoplasmic reticulum-Golgi intermediate compartment organization autophagosome maturation transport autophagy vesicle-mediated transport

Process(es)

SNARE binding SNAP receptor activity protein binding protein kinase binding protein phosphatase binding

Syntaxin 17 Polyclonal Antibody

Product Details

17815-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

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