Proteintech

Syntaxin 4 Polyclonal Antibody

View all (11) Syntaxin 4 antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

Syntaxin 4 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Rat kidney tissue were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Immunoprecipitation (IP) — IP result of anti-Syntaxin 4 (IP:14988-1-AP, 4ug; Detection:14988-1-AP 1:1500) with mouse kidney tissue lysate 4000ug.

Product Details

14988-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	View 3 publications 3 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Syntaxin 4 Fusion Protein Ag6973 (1-272 aa encoded by BC002436) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.25 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MRDRTHELR QGDDSSDEED KERVALVVHP GTARLGSPDE EFFHKVRTIR QTIVKLGNKV QELEKQQVTI LATPLPEESM KQELQNLRDE IKQLGREIRL QLKAIEPQKE EADENYNSVN TRMRKTQHGV LSQQFVELIN KCNSMQSEYR EKNVERIRRQ LKITNAGMVS DEELEQMLDS GQSEVFVSNI LKDTQVTRQA LNEISARHSE IQQLERSIRE LHDIFTFLAT EVEMQGEMIN RIEKNILSSA DYVERGQEHV KTALENQKKA RKK (1-272 aa encoded by BC002436)

Target Information

STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing.

Frontiers in immunology

Lopez JA,Noori T,Minson A,Li Jovanoska L,Thia K,Hildebrand MS,Akhlaghi H,Darcy PK,Kershaw MH,Brown NJ,Grigg A,Trapani JA,Voskoboinik I

Fri May 10 00:00:00 EDT 2019

Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.

The Journal of biological chemistry

Aerbajinai W,Liu L,Zhu J,Kumkhaek C,Chin K,Rodgers GP

Fri Apr 15 00:00:00 EDT 2016

C-reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cells.

British journal of pharmacology

Bian F,Yang X,Zhou F,Wu PH,Xing S,Xu G,Li W,Chi J,Ouyang C,Zhang Y,Xiong B,Li Y,Zheng T,Wu D,Chen X,Jin S

Thu May 01 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: Renal carcinoma antigen NY-REN-31; syntaxin 4A (placental); Syntaxin-4

Gene Aliases: p35-2; STX4; STX4A; Syn-4; Syn4

UniProt ID: (Human) Q12846, (Rat) Q08850, (Mouse) P70452

Entrez Gene ID: (Human) 6810, (Rat) 81803, (Mouse) 20909

Molecular Function: SNARE protein

intracellular protein transport post-Golgi vesicle-mediated transport positive regulation of cell proliferation regulation of exocytosis positive regulation of cell migration synaptic vesicle fusion to presynaptic active zone membrane response to hydroperoxide SNARE complex assembly positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of catalytic activity positive regulation of eosinophil degranulation positive regulation of cell adhesion vesicle docking organelle fusion positive regulation of chemotaxis positive regulation of immunoglobulin secretion long-term synaptic potentiation positive regulation of establishment of protein localization to plasma membrane regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to plasma membrane positive regulation of protein localization to cell surface protein complex assembly synaptic vesicle docking intracellular transport membrane fusion transport neurotransmitter transport synaptic vesicle exocytosis vesicle-mediated transport

Process(es)

SNARE binding SNAP receptor activity protein binding sphingomyelin phosphodiesterase activator activity myosin binding Rab GTPase binding spectrin binding