Proteintech

Syntaxin 4 Polyclonal Antibody

View all (8) Syntaxin 4 antibodies

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Syntaxin 4 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Rat kidney tissue were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 14988-1-AP (Syntaxin 4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

Syntaxin 4 Antibody in Immunoprecipitation (IP) — IP result of anti-Syntaxin 4 (IP:14988-1-AP, 4ug; Detection:14988-1-AP 1:1500) with mouse kidney tissue lysate 4000ug.

Product Details

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

0.5-4.0 µg

-

Western Blot (WB)

1:500-1:3000

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Syntaxin 4 Fusion Protein Ag6973

Conjugate

Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Renal carcinoma antigen NY-REN-31; syntaxin 4A (placental); Syntaxin-4

Gene Aliases: p35-2; STX4; STX4A; Syn-4; Syn4

UniProt ID: (Human) Q12846, (Rat) Q08850, (Mouse) P70452

Entrez Gene ID: (Human) 6810, (Rat) 81803, (Mouse) 20909

Molecular Function: SNARE protein membrane traffic protein

intracellular protein transport post-Golgi vesicle-mediated transport positive regulation of cell proliferation regulation of exocytosis positive regulation of cell migration synaptic vesicle fusion to presynaptic active zone membrane response to hydroperoxide SNARE complex assembly positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of catalytic activity positive regulation of eosinophil degranulation positive regulation of cell adhesion vesicle docking organelle fusion positive regulation of chemotaxis positive regulation of immunoglobulin secretion long-term synaptic potentiation positive regulation of establishment of protein localization to plasma membrane regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to plasma membrane positive regulation of protein localization to cell surface protein complex assembly synaptic vesicle docking intracellular transport membrane fusion transport neurotransmitter transport synaptic vesicle exocytosis vesicle-mediated transport

Process(es)

SNARE binding SNAP receptor activity protein binding sphingomyelin phosphodiesterase activator activity myosin binding Rab GTPase binding spectrin binding