Invitrogen

Syntaxin 4 Polyclonal Antibody

View all (13) Syntaxin 4 antibodies

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Questions & Answers

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Syntaxin 4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of Syntaxin 4 in paraffin-embedded rat pancreas. Samples were probed with Syntaxin 4 polyclonal antibody (Product # PA5-77513) using a dilution of 1:100, and incubated with hematoxylin.

Syntaxin 4 Antibody in Western Blot (WB) — Western blot analysis of rat heart lysate with Syntaxin 4 polyclonal antibody (Product # PA5-77513) using a dilution of 1:400.

Syntaxin 4 Antibody — RDRTHELRQGDNISDDEDEVRV(C), corresponding to residues 2-23 of rat Syntaxin 4

Product Details

PA5-77513

Applications	Tested Dilution	Publications
Western Blot (WB)	1:400	-
Immunohistochemistry (IHC)	1:100	-
Immunoprecipitation (IP)	10 µg/mL	-

Product Specifications
Species Reactivity	Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide RDRTHELRQGDNISDDEDEVRV(C), corresponding to residues 2-23 of rat Syntaxin 4 View antigen
Conjugate	Unconjugated
Form	Lyophilized
Concentration	0.4 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.4, with 1% BSA
Contains	0.05% sodium azide
Storage conditions	-20°C
RRID	AB_2736673

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: syntaxin 4A (placental); Syntaxin-4

Gene Aliases: Stx4; Stx4a; Syn-4; Syn4

UniProt ID: (Rat) Q08850, (Mouse) P70452

Entrez Gene ID: (Rat) 81803, (Mouse) 20909

Molecular Function: SNARE protein

protein complex assembly intracellular protein transport positive regulation of cell proliferation synaptic vesicle docking regulation of exocytosis positive regulation of cell migration synaptic vesicle fusion to presynaptic active zone membrane response to hydroperoxide SNARE complex assembly positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of catalytic activity positive regulation of eosinophil degranulation positive regulation of cell adhesion intracellular transport organelle fusion positive regulation of chemotaxis positive regulation of immunoglobulin secretion long-term synaptic potentiation membrane fusion positive regulation of establishment of protein localization to plasma membrane regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to plasma membrane positive regulation of protein localization to cell surface transport neurotransmitter transport synaptic vesicle exocytosis vesicle-mediated transport vesicle docking

Process(es)

SNARE binding SNAP receptor activity protein binding sphingomyelin phosphodiesterase activator activity Rab GTPase binding spectrin binding