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Proteintech
Syntaxin 6 Monoclonal Antibody (2B6G4), CoraLite® Plus 488
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Product Details
CL488-60059
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2B6G4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSMEDPFFVV KGEVQKAVNT AQGLFQRWTE LLQDPSTATR EEIDWTTNEL RNNLRSIEWD LEDLDETISI VEANPRKFNL DATELSIRKA FITSTRQVVR DMKDQMSTSS VQALAERKNR QALLGDSGSQ NWSTGTTDKY GRLDRELQRA NSHFIEEQQA QQQLIVEQQD EQLELVSGSI GVLKNMSQRI GGELEEQAVM LEDFSHELES TQSRLDNVMK KLAKVSHMTS DRRQWCAIAI LFAVLLVVLI LFLVL
Target Information
Syntaxin 6 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:11441; STX6; Syn6; Syntaxin-6; unnamed protein product
Gene Aliases: 2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; STX6
UniProt ID: (Human) O43752, (Mouse) Q9JKK1, (Rat) Q63635
Entrez Gene ID: (Human) 10228, (Mouse) 58244, (Rat) 60562
intracellular protein transport
vesicle fusion
endosome organization
protein transport
synaptic vesicle to endosome fusion
vesicle-mediated transport
endocytic recycling
regulation of protein localization
retrograde transport, endosome to Golgi
Golgi vesicle transport
vesicle docking
transport
Golgi ribbon formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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