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Invitrogen
Syntaxin 6 Recombinant Rabbit Monoclonal Antibody (821L4)
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FIGURE: 1 / 5
Syntaxin 6 Antibody (701823) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized MCF-7 cells for detection of Syntaxin-6 using Anti-Syntaxin-6 Recombinant Rabbit Monoclonal Antibody (Product # 701823, 1 µg/mL), alpha-Tubulin Monoclonal Antibody (Product # 32-2500, 1 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000), Goat anti-Mouse Ig... View More
Product Details
701823
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
821L4
Immunogen
Recombinant protein corresponding to Human STX6 (aa 2-234)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Bovine, Rat and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Syntaxin 6 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:11441; Syn6; Syntaxin-6
Gene Aliases: 2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; STX6
UniProt ID: (Human) O43752, (Mouse) Q9JKK1, (Rat) Q63635
Entrez Gene ID: (Human) 10228, (Mouse) 58244, (Rat) 60562
intracellular protein transport
vesicle fusion
endosome organization
endocytic recycling
regulation of protein localization
retrograde transport, endosome to Golgi
Golgi vesicle transport
vesicle docking
Golgi ribbon formation
regulation of cellular protein localization
transport
protein transport
vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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