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Product Details
12322-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat,
Human
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Syntaxin 7 Fusion Protein Ag2975 (1-244 aa encoded by BC011975)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSYTPGVGG DPAQLAQRIS SNIQKITQCS VEIQRTLNQL GTPQDSPELR QQLQQKQQYT NQLAKETDKY IKEFGSLPTT PSEQRQRKIQ KDRLVAEFTT SLTNFQKVQR QAAEREKEFV ARVRASSRVS GSFPEDSSKE RNLVSWESQT QPQVQVQDEE ITEDDLRLIH ERESSIRQLE ADIMDINEIF KDLGMMIHEQ GDVIDSIEAN VENAEVHVQQ ANQQLSRAAD YQRKSRKTLC IIILI (1-244 aa encoded by BC011975)
Target Information
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Syntaxin-7; Syntaxin7
Gene Aliases: AI315064; AI317144; AW107239; STX7; Syn7
UniProt ID: (Human) O15400, (Rat) O70257
Entrez Gene ID: (Human) 8417, (Rat) 60466, (Mouse) 53331
positive regulation of T cell mediated cytotoxicity
intracellular protein transport
vesicle fusion
vesicle docking
organelle localization
organelle assembly
positive regulation of receptor localization to synapse
regulation of protein localization to plasma membrane
endosome to lysosome transport
synaptic vesicle exocytosis
vesicle-mediated transport
membrane fusion
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