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OriGene
KATNB1 Monoclonal Antibody (OTI5H6), TrueMAB™
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FIGURE: 1 / 2
KATNB1 Antibody (TA503750) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KATNB1 (RC201852, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-KATNB. Positive lysates LY417004 (100 µg) and LC417004 (20 µg) can be purchased separately from OriGene.
Product Details
TA503750
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI5H6
Immunogen
Full length human recombinant protein of human KATNB1 produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Amount
67 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: katanin (80 kDa); katanin p80 (WD repeat containing) subunit B 1; katanin p80 (WD40-containing) subunit B 1; Katanin p80 subunit B1; Katanin p80 WD40 repeat-containing subunit B1; katanin p80 WD40-containing subunit B1; KATNB1; p80 katanin
Gene Aliases: KAT; KATNB1; LIS6
UniProt ID: (Human) Q9BVA0
Entrez Gene ID: (Human) 10300
protein targeting
microtubule depolymerization
negative regulation of microtubule depolymerization
mitotic chromosome movement towards spindle pole
positive regulation of neuron projection development
positive regulation of microtubule depolymerization
cytoplasmic microtubule organization
positive regulation of apoptotic process
microtubule severing
cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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