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OriGene
AKT2 Monoclonal Antibody (OTI1A2), Biotin, TrueMAB™
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Product Details
TA700010
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI1A2
Immunogen
Full length human recombinant protein of human AKT2 produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 10mg/mL BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
AKT2 is a phosphoinositide-dependent serine/threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone. Akt is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: murine thymoma viral (v-akt) homolog-2; PKB beta; Protein kinase Akt-2; Protein kinase B beta; putative v-akt murine thymoma viral oncoprotein 2; RAC protein kinase beta; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; unnamed protein product; v-akt murine thymoma viral oncogene homolog 2
Gene Aliases: AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
UniProt ID: (Human) P31751
Entrez Gene ID: (Human) 208
glycogen metabolic process
glycogen biosynthetic process
glucose metabolic process
regulation of translation
apoptotic process
signal transduction
insulin receptor signaling pathway
negative regulation of plasma membrane long-chain fatty acid transport
positive regulation of glucose metabolic process
regulation of cell migration
positive regulation of cell migration
positive regulation of fatty acid beta-oxidation
peripheral nervous system myelin maintenance
cellular response to insulin stimulus
intracellular signal transduction
protein modification process
negative regulation of apoptotic process
positive regulation of blood vessel endothelial cell migration
fat cell differentiation
positive regulation of glycogen biosynthetic process
positive regulation of glucose import
protein stabilization
regulation of cell cycle
mammary gland epithelial cell differentiation
cellular response to high light intensity
protein localization to plasma membrane
positive regulation of protein targeting to membrane
retinal rod cell apoptotic process
positive regulation of cap-dependent translational initiation
negative regulation of PERK-mediated unfolded protein response
positive regulation of cell motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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