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OriGene
LEPRE1 Monoclonal Antibody (OTI1B4), Biotin, TrueMAB™
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Product Details
TA700057
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1B4
Immunogen
Full length human recombinant protein of human LEPRE1 produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 10mg/mL BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth suppressor 1; leprecan; Leprecan-1; leucine proline-enriched proteoglycan (leprecan) 1; Leucine- and proline-enriched proteoglycan 1; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 1; unnamed protein product
Gene Aliases: GROS1; LEPRE1; OI8; P3H1; PSEC0109
UniProt ID: (Human) Q32P28
Entrez Gene ID: (Human) 64175
protein folding
negative regulation of cell proliferation
positive regulation of neuron projection development
protein hydroxylation
collagen fibril organization
regulation of ossification
negative regulation of cell growth
collagen metabolic process
regulation of protein secretion
protein stabilization
bone development
negative regulation of post-translational protein modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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