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OriGene
REV1 Monoclonal Antibody (OTI1E12), TrueMAB™
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FIGURE: 1 / 2
REV1 Antibody (TA811575S) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY REV1 (RC221742, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-REV1. (1. Positive lysates LY402538 (100 µg) and LC402538 (20 µg) can be purchased separately from OriGene.
Product Details
TA811575S
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1E12
Immunogen
Human recombinant protein fragment corresponding to amino acids 1079-1251 of human REV1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AIBP80; Alpha integrin-binding protein 80; DNA repair protein REV1; REV1 homolog; REV1, polymerase (DNA directed); REV1- like; Rev1-like terminal deoxycytidyl transferase
Gene Aliases: AIBP80; REV1; REV1L
UniProt ID: (Human) Q9UBZ9
Entrez Gene ID: (Human) 51455, (Rat) 316344
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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