Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.
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Protein Aliases: EKA; EKA/B; EKC; endokinin; Endokinin-A; Endokinin-A/B; Endokinin-C; PPT-C; Preprotachykinin-C; TAC4; TAC4 (HGNC:16641); Tachykinin-4
Gene Aliases: EK; HK-1; HK1; PPT-C; TAC4
UniProt ID: (Human) Q86UU9
Entrez Gene ID: (Human) 255061