Immunogen sequence: YCCLNKRFRA GFKRAFRWCP FIKVSSYDEL ELKTTRFHPN RQSSMYTVTR MESMTVVFDP NDADTTRSSR KKRATPRDPS FNGCSRRNSK SASATSSFIS SPYTSVDEYS; Positive Samples: HL-60, Human placenta; Cellular Location: Cell membrane, Multi-pass membrane protein
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
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Protein Aliases: neurokinin 3 receptor; Neurokinin B receptor; neurokinin beta receptor; neuromedin K receptor; Neuromedin K receptor (Neurokinin B/Tachikin 3); Neuromedin-K receptor; NK-3 receptor; NK-3R; Nk3 receptor; NKR; tachikin receptor 3; Tachykinin receptor 3
Gene Aliases: HH11; NK-3R; NK3R; NKR; Nmkr; TAC3R; TAC3RL; TACR3