Peptide sequence: YEVSEEEEDE EEEEQRSGPS VLSQVHLSED EEDSEDFHSI AGDSDLDSDE
Sequence homology: Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%
3-Phosphoglycerate dehydrogenase (PHGDH; EC 220.127.116.11) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BA2R; CCG1; CCGS; Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; DYT3; DYT3/TAF1; KAT4; N-TAF1; NSCL2; OF; P250; TAF(II)250; TAF1 RNA polymerase II; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform; TAF2A; TATA box binding protein associated factor 1; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; Transcription initiation factor TFIID subunit 1; XDP
Gene Aliases: AU015687; B430306D02Rik; BA2R; Ccg-1; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; RGD1562050; TAF(II)250; TAF1; TAF2A; TAFII-250; TAFII250; XDP