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Proteintech
TAF11 Polyclonal Antibody
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Product Details
16114-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAF11 Fusion Protein Ag9039 (1-211 aa encoded by BC021972)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDDAHESPS DKGGETGESD ETAAVPGDPG ATDTDGIPEE TDGDADVDLK EAAAEEGELE SQDVSDLTTV EREDSSLLNP AAKKLKIDTK EKKEKKQKVD EDEIQKMQIL VSSFSEEQLN RYEMYRRSAF PKAAIKRLIQ SITGTSVSQN VVIAMSGISK VFVGEVVEEA LDVCEKWGEM PPLQPKHMRE AVRRLKSKGQ IPNSKHKKII FF (1-211 aa encoded by BC021972)
Target Information
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TAF(II)28; TAF11; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; TAFII-28; TAFII28; TATA box binding protein (TBP)-associated factor 11; TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; Transcription initiation factor TFIID 28 kDa subunit; Transcription initiation factor TFIID subunit 11; unnamed protein product
Gene Aliases: 1110038O14Rik; 28kDa; AI115401; AL024207; AW552398; MGC:15243; PRO2134; PRO214; TAF11; TAF2I; TAFII28
UniProt ID: (Human) Q15544, (Mouse) Q99JX1, (Rat) Q5U1X0
Entrez Gene ID: (Human) 6882, (Mouse) 68776, (Rat) 309638
transcription coactivator activity
protein binding
obsolete general RNA polymerase II transcription factor activity
TBP-class protein binding
vitamin D receptor binding
thyroid hormone receptor binding
protein heterodimerization activity
DNA binding
transcription factor binding
protein N-terminus binding
molecular_function
general transcription factor
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
mRNA transcription from RNA polymerase II promoter
positive regulation by host of viral transcription
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of nucleic acid-templated transcription
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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