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Proteintech
TAF5L Polyclonal Antibody
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Product Details
19274-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAF5L Fusion Protein Ag5942 (1-325 aa encoded by BC041094)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKRVRTEQI QMAVSCYLKR RQYVDSDGPL KQGLRLSQTA EEMAANLTVQ SESGCANIVS AAPCQAEPQQ YEVQFGRLRN FLTDSDSQHS HEVMPLLYPL FVYLHLNLVQ NSPKSTVESF YSRFHGMFLQ NASQKDVIEQ LQTTQTIQDI LSNFKLRAFL DNKYVVRLQE DSYNYLIRYL QSDNNTALCK VLTLHIHLDV QPAKRTDYQL YASGSSSRSE NNGLEPPDMP SPILQNEAAL EVLQESIKRV KDGPPSLTTI CFYAFYNTEQ LLNTAEISPD SKLLAAGFDN SCIKLWSLRS KKLKSEPHQV DVSRIHLACD ILEEEV (1-325 aa encoded by B C041094)
Target Information
TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PAF65-beta; PCAF-associated factor 65 beta; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF5L
Gene Aliases: 1110005N04Rik; AI849020; PAF65B; TAF5L
UniProt ID: (Human) O75529, (Mouse) Q91WQ5
Entrez Gene ID: (Human) 27097, (Mouse) 102162, (Rat) 307927
transcription, DNA-templated
regulation of transcription, DNA-templated
histone H3 acetylation
regulation of nucleic acid-templated transcription
regulation of DNA repair
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of RNA splicing
positive regulation of transcription, DNA-templated
regulation of somatic stem cell population maintenance
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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