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Product Details
PA5-28205
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 288 of Human TAF7
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545681
Product Specific Information
Recommended positive controls: A431, JurkatHeLa, HepG2, A431, Jurkat.
Predicted reactivity: Mouse (89%), Rat (91%), Chicken (86%), Rhesus Monkey (100%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA polymerase II TBP-associated factor subunit F; TAF(II)55; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; TAFII-55; TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD; TATA box binding protein associated factor 7; TBP-associated factor F; transcription factor IID subunit TAFII55; Transcription initiation factor TFIID 55 kDa subunit; Transcription initiation factor TFIID subunit 7; transcription initiation factor TFIID, 55 kDa subunit
Gene Aliases: TAF2F; TAF7; TAFII55
UniProt ID: (Human) Q15545
Entrez Gene ID: (Human) 6879
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
histone acetyltransferase binding
vitamin D receptor binding
transcription regulatory region DNA binding
thyroid hormone receptor binding
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
spermine transport
DNA-templated transcription, initiation
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
negative regulation of protein kinase activity
intracellular estrogen receptor signaling pathway
negative regulation of histone acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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