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Invitrogen
TAF9 Polyclonal Antibody
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Product Details
PA5-72802
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAF9 antibody for a 17 amino acid peptide near the center of human TAF9. The immunogen is within amino acids 110 - 160 of TAF9.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD-004; CGI-137; CIP; hCINAP; MGC:1603; MGC:3647; RNA polymerase II TBP-associated factor subunit G; STAF31/32; TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32 kDa; TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa; TAF9 RNA polymerase II, TATA box binding protein-associated factor; taf9 {ECO:0000312|EMBL:AAH91109.1}; TAFII-31; TAFII-32; transcription initiation factor TFIID 31 kD subunit; Transcription initiation factor TFIID 31 kDa subunit; Transcription initiation factor TFIID 32 kDa subunit; Transcription initiation factor TFIID subunit 9
Gene Aliases: 2310012M09Rik; AA673500; AU045423; CINAP; MGC:5067; STAF31/32; TAF2G; TAF9; TAFII-31; TAFII-32; TAFII31; TAFII32; TAFIID32
UniProt ID: (Human) Q16594, (Rat) Q5BKE0, (Mouse) Q8VI33
Entrez Gene ID: (Human) 6880, (Rat) 373541, (Mouse) 108143
transcription regulatory region sequence-specific DNA binding
p53 binding
DNA binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
obsolete general RNA polymerase II transcription factor activity
protein heterodimerization activity
ATPase binding
C2H2 zinc finger domain binding
DNA-binding transcription factor binding
activating transcription factor binding
transcription regulatory region DNA binding
box C/D snoRNP assembly
regulation of DNA repair
chromatin remodeling
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
mRNA transcription from RNA polymerase II promoter
negative regulation of apoptotic process
regulation of RNA splicing
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein stabilization
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
positive regulation of response to cytokine stimulus
response to interleukin-1
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of cell growth
histone H3 acetylation
response to L-glutamate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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