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Invitrogen
TAGAP Polyclonal Antibody
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FIGURE: 1 / 1
TAGAP Antibody (PA5-75939) in WB
Western blot analysis of TAGAP in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: PC12 whole cell lysate (40 µg), Lane 3: RAW264.7 whole cell lysate (40 µg), Lane 4: MCF-7 whole cell lysate (40 µg), Lane 5: H9C2 whole cell lysate (40 µg). Samples were incubated with TAGAP polyclonal antibody (Product # PA5-75939) at a dilution of 1:500.
Product Details
PA5-75939
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 186-231 of Human TAGAP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP may function as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases and maps to human chromosome 6q25.3. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency and maple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: T-cell activation GTPase activating protein; T-cell activation GTPase-activating protein; T-cell activation GTPase-activating protein 1; T-cell activation Rho GTPase-activating protein
Gene Aliases: 2610315E15Rik; ARHGAP47; FKSG15; IDDM21; TAGAP; TAGAP1
UniProt ID: (Human) Q8N103, (Mouse) B2RWW0
Entrez Gene ID: (Human) 117289, (Mouse) 72536, (Rat) 308097
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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