This antibody is predicted to react with bovine and canine based on sequence homology.
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: 22 kDa actin-binding protein; Actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; SM22; SM22-alpha; Sm22alpha; SMCC; smooth muscle 22 protein; Smooth muscle protein 22-alpha; TAGLN; TAGLN1; Transgelin; transgelin variant 2; WS3-10
Gene Aliases: SM22; Sm22a; SMCC; TAGLN; TAGLN1; WS3-10; Ws310