Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody was generated against full length transgenlin 3 protein. It may cross-react with other two transgenlins based on the sequence similarity.
Immunogen sequence: MANRGPSYG LSREVQEKIE QKYDADLENK LVDWIILQCA EDIEHPPPGR AHFQKWLMDG TVLCKLINSL YPPGQEPIPK ISESKMAFKQ MEQISQFLKA AETYGVRTTD IFQTVDLWEG KDMAAVQRTL MALGSVAVTK DDGCYRGEPS WFHRKAQQNR RGFSEEQLRQ GQNVIGLQMG SNKGASQAGM TGYGMPRQIM (1-199 aa encoded by BC015329)
The transgelin family is a group of proteins that belong to 22 kDa actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neuronal protein 22; Neuronal protein NP25; NP22; Transgelin-3
Gene Aliases: 2700038H05Rik; 2900005O10Rik; AI426007; NP22; NP24; NP25; TAGLN3
UniProt ID: (Human) Q9UI15, (Mouse) Q9R1Q8, (Rat) P37805
Entrez Gene ID: (Human) 29114, (Mouse) 56370, (Rat) 63837
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