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Invitrogen
TAT complex Monoclonal Antibody (C1)
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TAT complex Antibody (MA5-51121) in WB
Western blot analysis of TAT complex in Human Serum. Samples were incubated with TAT complex monoclonal antibody (Product # MA5-51121) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG secondary antibody at a dilution of 0.2 µg/mL.
Product Details
MA5-51121
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C1
Immunogen
Recombinant Human TAT protein, Ile364-Glu622 + GGGGS*3 + His33-Lys464 (Accession #P00734 & P01008)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The Thrombin-antithrombin complex (TAT complex) is a protein complex formed by the binding of thrombin, a serine protease involved in blood clotting, and antithrombin, a serine protease inhibitor that regulates thrombin activity. This complex plays a crucial role in maintaining the balance between blood clotting and preventing excessive clotting, which can lead to thrombosis. The complex is formed when antithrombin binds to thrombin, inhibiting its activity and preventing the formation of blood clots.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antithrombin-III; ATIII; Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine protease; Serpin C1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; TAT
Gene Aliases: AT3; AT3D; ATIII; F2; PRO0309; PT; RPRGL2; SERPINC1; THPH1; THPH7
UniProt ID: (Human) P00734, (Human) P01008
Entrez Gene ID: (Human) 2147, (Human) 462
positive regulation of protein phosphorylation
signal peptide processing
proteolysis
ER to Golgi vesicle-mediated transport
acute-phase response
cell surface receptor signaling pathway
multicellular organism development
blood coagulation
blood coagulation, intrinsic pathway
positive regulation of cell proliferation
regulation of cell shape
response to wounding
regulation of gene expression
negative regulation of platelet activation
positive regulation of phosphatidylinositol 3-kinase signaling
response to inactivity
peptidyl-glutamic acid carboxylation
platelet activation
regulation of blood coagulation
positive regulation of blood coagulation
positive regulation of cell growth
positive regulation of collagen biosynthetic process
fibrinolysis
cellular protein metabolic process
negative regulation of proteolysis
negative regulation of astrocyte differentiation
leukocyte migration
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
negative regulation of fibrinolysis
cellular response to mechanical stimulus
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of reactive oxygen species metabolic process
response to nutrient
negative regulation of endopeptidase activity
negative regulation of inflammatory response
regulation of blood coagulation, intrinsic pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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