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Proteintech
TAX1BP3 Polyclonal Antibody
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Product Details
11692-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAX1BP3 Fusion Protein Ag2306 (1-124 aa encoded by BC023980)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Amount
70.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSYIPGQPV TAVVQRVEIH KLRQGENLIL GFSIGGGIDQ DPSQNPFSED KTDKGIYVTR VSEGGPAEIA GLQIGDKIMQ VNGWDMTMVT HDQARKRLTK RSEEVVRLLV TRQSLQKAVQ QSMLS (1-124 aa encoded by BC023980)
Target Information
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C20orf100; GCX1; GIP-3; Glutaminase-interacting protein 3; Tax interaction protein 1; Tax-interacting protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 3; Tax1 binding protein 3; Tax1-binding protein 3; tax1bp3; tax1bp3 {ECO:0000312|EMBL:AAH97976.1}; TIP-1; unnamed protein product
Gene Aliases: 1300011C24Rik; TAX1BP3; TIP-1; TIP1
UniProt ID: (Human) O14907, (Mouse) Q9DBG9, (Rat) Q4QQV1
Entrez Gene ID: (Human) 30851, (Mouse) 76281, (Rat) 360564
Rho protein signal transduction
negative regulation of cell proliferation
Wnt signaling pathway
regulation of Wnt signaling pathway
negative regulation of Wnt signaling pathway
activation of GTPase activity
negative regulation of protein localization to cell surface
regulation of Cdc42 protein signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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