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Invitrogen
TAZ Polyclonal Antibody
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FIGURE: 1 / 3
TAZ Antibody (PA5-114792) in IHC (P)
Immunohistochemistry analysis of TAZ in mouse muscle tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114792) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-114792
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TAZ(Accession Q16635), corresponding to amino acid residues G124-W174.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total TAZ.
Target Information
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acyltransferase; Barth syndrome); cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; tafazzin (cardiomyopathy, dilated 3A (X-linked); tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome); Taz; unnamed protein product; XAP-2; XX-FW83563B9.3
Gene Aliases: 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q5HY44, (Mouse) Q91WF0
Entrez Gene ID: (Human) 6901, (Rat) 363521, (Mouse) 66826
lipid metabolic process
phospholipid metabolic process
inner mitochondrial membrane organization
cardiolipin acyl-chain remodeling
cristae formation
positive regulation of cardiolipin metabolic process
positive regulation of ATP biosynthetic process
muscle contraction
heart development
skeletal muscle tissue development
biological_process
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
phosphatidylglycerol metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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