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Proteintech
TBL3 Polyclonal Antibody
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Product Details
31150-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBL3 fusion protein Ag34900
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TIKNNECVRT LDAHEDKVWG LHCSRLDDHA LTGASDSRVI LWKDVTEAEQ AEEQARQEEQ VVRQQELDNL LHEKRYLRAL GLAISLDRPH TVLTVIQAIR RDPEACEKLE ATMLRLRRDQ KEALLRFCVT
Target Information
WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: transducin (beta)-like 3; Transducin beta-like protein 3; WD repeat-containing protein SAZD; WD-repeat protein SAZD
Gene Aliases: 9430070M15Rik; SAZD; TBL3; UTP13
UniProt ID: (Human) Q12788, (Mouse) Q8C4J7
Entrez Gene ID: (Human) 10607, (Mouse) 213773
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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