Invitrogen

TBPL1 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (6) TBPL1 antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

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TBPL1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of TBPL1 in SK-MEL-30 cells using a TBPL1 polyclonal antibody (Product # PA5-84876). The analysis shows localization to nucleus & nucleoli.

TBPL1 Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of TBPL1 in human testis and liver tissues using a TBPL1 polyclonal antibody (Product # PA5-84876). Corresponding RNA-seq data are presented for the same tissues.

TBPL1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of TBPL1 demonstrates antibody specificity. Immunohistochemical analysis of TBPL1 using anti-TBPL1 Polyclonal Antibody (Product #PA5-84876), shows significant staining of TBPL1 in testis and shows minimal or weak staining in liver tissues. The relative expression levels of TBPL1 within each tissue is shown using RNA-Seq.

Product Details

PA5-84876

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TBPL1

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Anitgen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2792025

Product Specific Information

Immunogen sequence: DADSDVALDI LITNVVCVFR TRCHLNLRKI ALEGANVIYK RDVGKVLMKL RKPRITATIW SSGKIICTGA TSEEEAKFGA RR

Target Information

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 21 kDa TBP-like protein; 21-kDA TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-like 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-like factor; TBP-like protein; TBP-related factor 2; TBP-related protein

Gene Aliases: MGC:8389; MGC:9620; STUD; TBPL1; TLF; TLP; TLP21; TRF2; TRP

UniProt ID: (Human) P62380

Entrez Gene ID: (Human) 9519

Molecular Function: general transcription factor