This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: DADSDVALDI LITNVVCVFR TRCHLNLRKI ALEGANVIYK RDVGKVLMKL RKPRITATIW SSGKIICTGA TSEEEAKFGA RR
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 21 kDa TBP-like protein; 21-kDA TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-like 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-like factor; TBP-like protein; TBP-related factor 2; TBP-related protein
Gene Aliases: MGC:8389; MGC:9620; STUD; TBPL1; TLF; TLP; TLP21; TRF2; TRP
UniProt ID: (Human) P62380
Entrez Gene ID: (Human) 9519
Molecular Function: general transcription factor