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Product Details
27159-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBXA2R Fusion Protein Ag25670
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Prostanoid TP receptor; Thromboxane A2 receptor; thromboxane prostanoid; TXA2 receptor; TXA2-R
Gene Aliases: BDPLT13; TBXA2R; TP; TXA2-R
UniProt ID: (Human) P21731, (Mouse) P30987
Entrez Gene ID: (Human) 6915, (Mouse) 21390
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to nutrient
second-messenger-mediated signaling
response to lipopolysaccharide
thromboxane A2 signaling pathway
response to drug
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
signal transduction
regulation of vasoconstriction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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