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Proteintech
TBXA2R Polyclonal Antibody
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Product Details
27159-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBXA2R Fusion Protein Ag25670
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G-protein coupled receptor; TBXA2R; Prostanoid TP receptor; Thromboxane A2 receptor; thromboxane prostanoid; TXA2 receptor; TXA2-R
Gene Aliases: BDPLT13; TBXA2R; TP; TXA2-R
UniProt ID: (Human) P21731, (Mouse) P30987
Entrez Gene ID: (Human) 6915, (Mouse) 21390
smooth muscle contraction
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to nutrient
response to xenobiotic stimulus
regulation of vasoconstriction
positive regulation of blood coagulation
response to lipopolysaccharide
response to testosterone
thromboxane A2 signaling pathway
response to ethanol
positive regulation of angiogenesis
positive regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
cellular response to lipopolysaccharide
negative regulation of cell migration involved in sprouting angiogenesis
second-messenger-mediated signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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