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Proteintech
TBXAS1 Polyclonal Antibody
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Product Details
30215-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: NKNRDELNGF FNKLIRNVIA LRDQQAAEER RRDFLQMVLD ARHSASPMGV QDFDIVRDVF SSTGCKPNPS RQHQPSPMAR PLTVDEIVGQ
Target Information
Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytochrome P450 5A1; cytochrome P450, family 5, subfamily A, polypeptide 1; FLJ52771; Hydroperoxy icosatetraenoate dehydratase; platelet, cytochrome P450, subfamily V; thromboxane A synthase 1 (platelet); Thromboxane-A synthase; TXA synthase
Gene Aliases: BDPLT14; CYP5; CYP5A1; GHOSAL; TBXAS1; THAS; TS; TXAS; TXS
UniProt ID: (Human) E7EMU9
Entrez Gene ID: (Human) 6916
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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