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Proteintech
TC10 Polyclonal Antibody
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Product Details
17805-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TC10 Fusion Protein Ag12078 (1-205 aa encoded by BC070485)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAHGPGALM LKCVVVGDGA VGKTCLLMSY ANDAFPEEYV PTVFDHYAVS VTVGGKQYLL GLYDTAGQED YDRLRPLSYP MTDVFLICFS VVNPASFQNV KEEWVPELKE YAPNVPFLLI GTQIDLRDDP KTLARLNDMK EKPICVEQGQ KLAKEIGACC YVECSALTQK GLKTVFDEAI IAILTPKKHT VKKRIGSRCI NCCLIT (1-205 aa encoded by B C070485)
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory protein Li 42; ras homolog gene family, member Q; ras-like protein; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; Rho-related GTP-binding protein RhoQ; small GTPase Tc10
Gene Aliases: ARHQ; HEL-S-42; RASL7A; RHOQ; TC10; TC10A
UniProt ID: (Human) P17081, (Mouse) Q8R527, (Rat) Q9JJL4
Entrez Gene ID: (Human) 23433, (Mouse) 104215, (Rat) 85428
endocytosis
actin filament organization
signal transduction
small GTPase mediated signal transduction
insulin receptor signaling pathway
regulation of cell shape
establishment of cell polarity
actin cytoskeleton organization
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
positive regulation of filopodium assembly
negative regulation of protein localization to plasma membrane
negative regulation of glucose import
negative regulation of establishment of protein localization to plasma membrane
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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