Immunogen sequence: KLLDGPSTEK DLDEKKKEPA ITSQNSPEAR EESTSSGNVS NRKDETNARD TYVSSFPRAP STSDSVRLKC RE
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: transcription elongation factor A (SII), 1; Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1; Transcription elongation factor TFIIS.o; transcription factor IIS
Gene Aliases: GTF2S; S-II; SII; TCEA; TCEA1; Tceat; TF2S; TFIIS
Molecular Function: general transcription factor