|Tested species reactivity||Rat, Human, Bovine|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide between amino acids 100-179 of the human TCF21 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||citric acid, pH 7-8|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is expected to react with mouse and xenopus proteins based on a 90% sequence homology.
Suggested positive control: Hela whole cell extract, antigen standard for TCF21 (transient overexpression lysate).
The basic helix-loop-helix transcription factor TCF21/Pod1 (also called capsulin or epicardin) is involved in kidney, lung and spleen organogenesis. It is also essential for normal development of the testes and ovaries. TCF21/Pod1 is involved in the transcriptional repression of steroidogenic factor 1 (Sf1/Nr5a1/Ad4BP), an orphan nuclear receptor that regulates the expression of multiple genes (including Scc) that mediate sexual differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.