|Western Blot (WB)||2 µg/ml|
|Tested Species reactivity||Rat, Human, Bovine|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide between amino acids 100-179 of the human TCF21 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||citric acid, pH 7-8|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is expected to react with mouse and xenopus proteins based on a 90% sequence homology.
Suggested positive control: Hela whole cell extract, antigen standard for TCF21 (transient overexpression lysate).
The basic helix-loop-helix transcription factor TCF21/Pod1 (also called capsulin or epicardin) is involved in kidney, lung and spleen organogenesis. It is also essential for normal development of the testes and ovaries. TCF21/Pod1 is involved in the transcriptional repression of steroidogenic factor 1 (Sf1/Nr5a1/Ad4BP), an orphan nuclear receptor that regulates the expression of multiple genes (including Scc) that mediate sexual differentiation.
Protein Aliases: capsulin; class A basic helix-loop-helix protein 23; epicardin; Epicardin Capsulin antibody.; pod-1; Pod-1 antibody; podocyte-expressed 1; Podocyte-expressed 1 antibody; TCF-21; transcription factor 21; Transcription factor 21 antibody
Gene Aliases: bHLHa23; BOS_9830; Capsulin; Msf-1; POD1