Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Fruit fly, Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
TCF4 Fusion Protein Ag17813 (407-560 aa encoded by BC125084) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.21 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: PSTAMPGGH GDMHGIIGPS HNGAMGGLGS GYGTGLLSAN RHSLMVGTHR EDGVALRGSH SLLPNQVPVP QLPVQSATSP DLNPPQDPYR GMPPGLQGQS VSSGSSEIKS DDEGDENLQD TKSSEDKKLD DDKKDIKSIT RSRSSNNDDE DLTPE (407-560 aa encoded by BC125084)
TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG')-a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHb19; Class A helix-loop-helix transcription factor ME2; Class B basic helix-loop-helix protein 19; E2 2; Immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF 2; ITF-2; MGC149723; MGC149724; MITF-2; SEF 2; SEF-2; SEF2 1; SEF2 1A; SEF2 1B; SL3-3 enhancer factor 2; TCF 4; TCF-4; Transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R
Gene Aliases: 5730422P05Rik; ASP-I2; BHLHB19; E2-2; E2.2; FECD3; ITF-2; ITF-2b; ITF2; ME2; MITF-2A; MITF-2B; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4; TCF4; TFE
UniProt ID: (Human) P15884, (Mouse) Q60722
Entrez Gene ID: (Human) 6925, (Mouse) 21413
Molecular Function:
basic helix-loop-helix transcription factor
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