Proteintech

TCF4 Polyclonal Antibody

Product Image Gallery

TCF4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human testis slide using 22337-1-AP ( TCF4 Antibody) at dilution of 1:200.

TCF4 Antibody in Western Blot (WB) — Mouse lung tissue were subjected to SDS PAGE followed by western blot with 22337-1-AP (TCF4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

TCF4 Antibody in Immunoprecipitation (IP) — IP result of anti-TCF4 (IP:22337-1-AP, 4ug; Detection:22337-1-AP 1:500) with mouse lung tissue lysate 4000ug.

Product Details

Applications

Tested Dilution

Publications

Immunofluorescence (IF)

Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunoprecipitation (IP)

0.5-4.0 µg

Western Blot (WB)

1:500-1:2000

View 4 publications 4 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Fruit fly, Human, Mouse

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TCF4 Fusion Protein Ag17813

Conjugate

Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG')-a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: bHLHb19; Class A helix-loop-helix transcription factor ME2; Class B basic helix-loop-helix protein 19; E2 2; Immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF 2; ITF-2; MGC149723; MGC149724; MITF-2; SEF 2; SEF-2; SEF2 1; SEF2 1A; SEF2 1B; SL3-3 enhancer factor 2; TCF 4; TCF-4; Transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R

Gene Aliases: 5730422P05Rik; ASP-I2; BHLHB19; E2-2; E2.2; FECD3; ITF-2; ITF-2b; ITF2; ME2; MITF-2A; MITF-2B; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4; TCF4; TFE

UniProt ID: (Human) P15884, (Mouse) Q60722

Entrez Gene ID: (Human) 6925, (Mouse) 21413

Molecular Function: basic helix-loop-helix transcription factor nucleic acid binding transcription factor