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Proteintech
TCF7L1 Polyclonal Antibody
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Product Details
14519-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TCF7L1 Fusion Protein Ag5983 (238-587 aa encoded by BC058894)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GAVGQIPHP LGWLVPQQGQ PMYSLPPGGF RHPYPALAMN ASMSSLVSSR FSPHMVAPAH PGLPTSGIPH PAIVSPIVKQ EPAPPSLSPA VSVKSPVTVK KEEEKKPHVK KPLNAFMLYM KEMRAKVVAE CTLKESAAIN QILGRKWHNL SREEQAKYYE LARKERQLHS QLYPTWSARD NYGKKKKRKR EKQLSQTQSQ QQVQEAEGAL ASKSKKPCVQ YLPPEKPCDS PASSHGSMLD SPATPSAALA SPAAPAATHS EQAQPLSLTT KPETRAQLAL HSAAFLSAKA AASSSRQMGS QPPLLSRPLP LGSMPTALLA SPPSFPATLH AHQALPVLQA QPLSLVTKSA H (238-587 aa encoded by BC058894)
Target Information
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HMG box transcription factor 3; T-cell factor 3; TCF-3; transcription factor 3; Transcription factor 7-like 1; transcription factor 7-like 1 (T-cell specific, HMG box); transcription factor 7-like 1 (T-cell specific, HMG-box); transcription factor 7-like 2 (T-cell specific, HMG box)
Gene Aliases: bHLHb21; TCF-3; TCF3; TCF7L1
UniProt ID: (Human) Q9HCS4, (Mouse) Q9Z1J1
Entrez Gene ID: (Human) 83439, (Rat) 312451, (Mouse) 21415
chromatin organization
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
regulation of Wnt signaling pathway
canonical Wnt signaling pathway
beta-catenin-TCF complex assembly
biological_process
anterior/posterior axis specification, embryo
somatic stem cell population maintenance
skin development
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter during mitosis
axial mesoderm morphogenesis
stem cell differentiation
regulation of stem cell population maintenance
Wnt signaling pathway
generation of neurons
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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