Immunogen sequence: MEAFRQKAEL GRFLRHQYNA QLSRRTQQIQ EELEADRRIL QALLEKEDES QRLHLARREQ VMADVAWMKQ AIEEQ
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
TCHP may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. This protein may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mitochondrial protein with oncostatic activity; Mitostatin; Protein TCHP; TCHP; TpMs; Trichoplein keratin filament-binding protein; trichoplein, keratin filament binding; Tumor suppressor protein
Gene Aliases: TCHP; TpMs
UniProt ID: (Human) Q9BT92
Entrez Gene ID: (Human) 84260