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Invitrogen
TCP-1 delta Polyclonal Antibody
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Product Details
PA5-93048
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 130-390 of human CCT4 (NP_0064212)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
35 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PTIISESFQK ALEKGIEILT DMSRPVELSD RETLLNSATT SLNSKVVSQY SSLLSPMSVN AVMKVIDPAT ATSVDLRDIK IVKKLGGTID DCELVEGLVL TQKVSNSGIT RVEKAKIGLI QFCLSAPKTD MDNQIVVSDY AQMDRVLREE RAYILNLVKQ IKKTGCNVLL IQKSILRDAL SDLALHFLNK MKIMVIKDIE REDIEFICKT IGTKPVAHID QFTADMLGSA ELAEEVNLNG SGKLLKITGC ASPGKTVTIV V; Positive Samples: MCF7, THP-1, Mouse spleen; Cellular Location: Cytoplasm, Melanosome, centrosome, cilium basal body, cytoskeleton, microtubule organizing center
Target Information
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A45; CCT containing TCP-1-delta; CCT-delta; Chaperonin containing T-complex polypeptide 1 subunit 4; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1, subunit 4 (delta); chaperonin subunit 4 (delta); Stimulator of TAR RNA-binding; T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta; unnamed protein product
Gene Aliases: 2610204B21Rik; A45; C78323; CCT-DELTA; CCT4; CCTD; SRB
UniProt ID: (Human) P50991, (Mouse) P80315, (Rat) Q7TPB1
Entrez Gene ID: (Human) 10575, (Mouse) 12464, (Rat) 29374
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
scaRNA localization to Cajal body
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
toxin transport
chaperone mediated protein folding requiring cofactor
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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