Immunogen sequence: VPLSGNPGYV VGLPLAAGFQ PHKGSGIIQT TNRYGQLTIL HSTTEQDCLA LEGVRTPVLF GYTMQSGCKL RLTGALPCQL VAQ
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.
TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.
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Protein Aliases: Tectonic-1; UNQ9369/PRO34160, JBTS13, TECT1
Gene Aliases: JBTS13; TCTN1; TECT1; UNQ9369/PRO34160
UniProt ID: (Human) Q2MV58
Entrez Gene ID: (Human) 79600