Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:200-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
TDRD5 Fusion Protein Ag18896 (1-350 aa encoded by BC130532) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.39 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MSEQERIQE CLRKEIRSLL ISTKDGLSPQ ELEKEYLLMV GNHLPLRILG YRSTMELVLD MPDVVRVCPG AGGTVILKAI PDESTKGIAS LVAKQRSSHK LRNSMHKGRP SIYSGPRSHR RVPYRGSVAP ILPAVVKSEL KDLLALSPVL LSDFEKAFAK RFGRSFQYMQ YGFLSMFEVL NAASDVISVE QTRAGSLLML KKSVTEEKPR GCPAGKIFTQ PFRMKQGSYS TGFPVAKPCF SQPTSNMEPP KQIMSMEKTS KLNVVETSRL NHTEKLNQLE NTFKSVIAQI GPGGTISSEL KHKIKFVVSK FPEGLFISKL LGEYEVIFKE QLSPKKLGFL NVTELVGALS D (1-350 aa encoded by BC130532)
TDRD5, also named as Tudor domain-containing protein 5, is a 981 amino acid protein, which contains one Tudor domain and three HTH OST-type domains. TDRD5 localizes in the cytoplasm and belongs to the TDRD5 family. TDRD5 is required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testicular tissue protein Li 194; tudor domain containing protein 5; Tudor domain-containing protein 5
Gene Aliases: Gm103; TDRD5; TUDOR3
UniProt ID: (Human) Q6ZSK2, (Mouse) Q5VCS6
Entrez Gene ID: (Human) 163589, (Mouse) 214575
Molecular Function:
scaffold/adaptor protein
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