Invitrogen

TENC1 Polyclonal Antibody

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TENC1 Antibody in Western Blot (WB) — Western blot analysis of TENC1 in MCF7 whole cell lysates using a TENC1 Polyclonal Antibody (Product # PA5-67976).

Product Details

PA5-67976

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthesized peptide derived from human TENC1. View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	affinity chromatography
Storage buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C
RRID	AB_2691847

Product Specific Information

Predicted to react with Mouse samples.

Target Information

Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C1 domain-containing phosphatase and tensin homolog; C1 domain-containing phosphatase and tensin-like protein; C1-TEN; tensin like C1 domain containing phosphatase (tensin 2); tensin like C1 domain-containing phosphatase; Tensin-2; Tensin-like C1 domain-containing phosphatase

Gene Aliases: C1-TEN; C1TEN; KIAA1075; nep; nph; TENC1; TNS2

UniProt ID: (Human) Q63HR2, (Mouse) Q8CGB6

Entrez Gene ID: (Human) 23371, (Mouse) 209039

Molecular Function: non-motor actin binding protein

kidney development protein dephosphorylation negative regulation of cell proliferation response to muscle activity cellular homeostasis collagen metabolic process multicellular organism growth intracellular signal transduction multicellular organismal homeostasis

Process(es)

phosphoprotein phosphatase activity protein binding kinase binding metal ion binding receptor binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity protein kinase binding inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity