Invitrogen

TENC1 Polyclonal Antibody

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TENC1 Antibody in Western Blot (WB) — Western blot analysis of TENC1 in MCF7 whole cell lysates using a TENC1 Polyclonal Antibody (Product # PA5-67976).

Product Details

Tested Applications

Dilution

Western Blot (WB)

1:1000

Product Specifications

Species Reactivity

Human, Mouse

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human TENC1.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

RRID

AB_2691847

Product Specific Information

Predicted to react with Mouse samples.

Target Information

Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: C1 domain-containing phosphatase and tensin homolog; C1 domain-containing phosphatase and tensin-like protein; C1-TEN; C1TEN; tensin 2; tensin like C1 domain containing phosphatase (tensin 2); tensin like C1 domain-containing phosphatase; Tensin-2; Tensin-like C1 domain-containing phosphatase; TNS2

Gene Aliases: C1-TEN; C1TEN; KIAA1075; nep; nph; TENC1; TNS2

UniProt ID: (Human) Q63HR2, (Mouse) Q8CGB6

Entrez Gene ID: (Human) 23371, (Mouse) 209039

Molecular Function: hydrolase phosphatase protein phosphatase

kidney development protein dephosphorylation negative regulation of cell proliferation response to muscle activity cellular homeostasis collagen metabolic process multicellular organism growth intracellular signal transduction multicellular organismal homeostasis

Process(es)

phosphoprotein phosphatase activity protein binding kinase binding metal ion binding receptor binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity protein kinase binding inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity